Wheat Germ Extract Spermidine

What is Wheat Germ Extract Spermidine?

Wheat Germ Extract Spermidine refers to a concentrated form of spermidine derived from the germ of wheat grains. Spermidine is a naturally occurring polyamine involved in various cellular processes such as growth, proliferation, and autophagy (the process by which cells remove damaged components).

Spermidine Food Sources

Here are some of the richest natural food sources of spermidine:

• Wheat Germ
• Soybeans
• Mushrooms
• Legumes
• Cheese (especially aged cheeses)
• Broccoli
• Green Peppers
• Whole Grains
• Cauliflower
• Meat (especially organ meats)
• Seafood

How much spermidine is in wheat germ？

Wheat germ is known for its relatively high spermidine content compared to other foods. On average, wheat germ contains about 200-300 micrograms of spermidine per gram. This can vary depending on the wheat germ’s source and processing.

Spermidine Wheat Germ Benefits

• Promotes Longevity
• Cellular Health
• Supports Cognitive Function
• Cardiovascular Health

How Does Wheat Germ Extract Spermidine Work?

Autophagy is the body’s cleaning out damaged cells and regenerating newer, healthier cells. Spermidine promotes autophagy, often described as a “self-cleaning” mechanism at the cellular level.

Inducing autophagy, spermidine helps remove toxic proteins and dysfunctional cellular components, reducing oxidative stress and the potential for age-related diseases. This is one of the reasons spermidine is linked to longevity and anti-aging benefits.

Does spermidine belong to novel foods in Europe?

Spermidine, although naturally occurring in foods like wheat germ, was not widely consumed in isolated or concentrated forms before 1997, necessitating its classification as a novel food when used in high concentrations or specialized extracts.

Spermidine vs Spermine

Spermidine and spermine are naturally occurring polyamines essential in cellular processes, particularly cell growth, proliferation, and maintenance. Despite their similarities, they have distinct characteristics and functions:

1. Chemical Structure:

• Spermidine: It is a triamine with the formula C7H19N3. It consists of a chain of carbon atoms with three amino groups (–NH2).
• Spermine: It is a tetra-amine with the formula C10H26N4, having four amino groups and a longer carbon chain compared to spermidine.

2. Biological Functions:

• Spermidine:
  • Plays a crucial role in cell growth, proliferation, and differentiation.
  • Stimulates autophagy, a process where cells remove damaged components associated with aging and longevity.
  • Has protective effects on the cardiovascular system, brain health, and may help in cancer prevention.
  • Involved in regulating DNA and RNA stabilization.
• Spermine:
  • Stabilizes DNA and RNA, and is essential for maintaining proper cellular function.
  • Helps regulate ion channels, particularly calcium channels, playing a role in neurotransmission.
  • Plays a role in protecting cells from oxidative damage.
  • Also linked to immune modulation and has anti-inflammatory effects.

The Manufacturing Process of  Spermidine

Manufacturing fermented wheat germ extract (FWGE) focusing on spermidine enrichment involves several key steps.

• Wheat Germ Selection: High-quality wheat germ is chosen for its natural spermidine content.
• Pre-Treatment: Wheat germ is cleaned and ground for better extraction and fermentation.
• Fermentation: Lactic acid bacteria or yeast ferment the wheat germ to enhance spermidine bioavailability and produce additional beneficial compounds.
• Extraction: Fermented wheat germ undergoes solvent extraction to isolate spermidine.
• Concentration and Purification: Techniques like evaporation and ultrafiltration concentrate and purify spermidine.
• Standardization: The extract is standardized to ensure consistent spermidine content.
• Drying and Formulation: The extract is dried into powder and formulated into supplements.
• Quality Control and Packaging: Rigorous quality checks ensure safety and potency before packaging for distribution.

Wheat Germ Extract Spermidine Supplement

• Wheat germ extract spermidine is commonly available in dietary supplement form, usually as capsules or tablets, designed to provide a concentrated dose of spermidine.
• These supplements are often marketed for their potential anti-aging, cognitive, and heart health benefits.

Wheat Germ Extract Spermidine Dosage

• Wheat germ extract spermidine supplements derived from wheat germ extract are typically taken in doses ranging from 1 mg to 10 mg daily, depending on the product.
• While wheat germ naturally contains spermidine, concentrated extracts allow for more precise and higher doses than can be easily obtained through diet alone.

Where to buy Wheat Germ Extract Spermidine?

Nutraflux is recognized for its expertise in producing high-quality wheat germ extract spermidine that meets European Pharmacopoeia (EP) standards, ensuring consistent quality for global distribution. With extensive experience in production, Nutraflux adheres to stringent manufacturing processes that prioritize product efficacy, purity, and safety.