PalmitoylEthanolamide

Product Name PalmitoylEthanolamide
Other Name N-(2-hydroxyethyl)palmitate,N-(2-hydroxyethyl)palmitate
CAS Number 544-31-0
Molecular Formula C18H37NO2
Molecular Weight 299.5
Specifications 99%
Appearance/color White to off-white powder,Micronized powder,Water Dispersed Powder
Application Dietary supplement
Bulk Package 25kg/drum
OEM services Available upon specific requirement

OEM MOQ: 500 Units
Place of Origin: 
China
Bulk Package: 25kg/drum
Port: Shanghai, China
Payment terms: T/T, Letter of Credit, Western Union

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What is Palmitoylethanolamide ?

Palmitoylethanolamide is a naturally occurring fatty acid amide that belongs to the family of endocannabinoid-like compounds. It is produced in the body in response to inflammation and tissue damage and has been studied for its potential anti-inflammatory, pain-relieving, and neuroprotective effects.

PalmitoylEthanolamide (PEA) natural sources

PEA is found naturally in foods like egg yolk, soy lecithin, and peanuts and is also synthesized in the body.

Palmitoylethanolamide (PEA) Benefits

1. Chronic Pain Relief.PEA has shown potential in managing various types of chronic pain.

2. Anti-Inflammatory Effects.PEA is known for its ability to reduce inflammation by binding to specific receptors (like PPAR-α) that inhibit the production of pro-inflammatory mediators.

3. Neuroprotective Properties.PEA may protect nerve cells and support brain health, which has led to its investigation into neurodegenerative diseases.

4. Supporting Immune Health.PEA has shown the potential to modulate the immune system and reduce excessive immune responses that cause inflammation.

5. Reducing Skin Inflammation and Itching.PEA has been used in topical formulations to reduce skin inflammation and itching, especially in conditions like eczema, dermatitis, and psoriasis.

How Does PEA work?

PEA powder binds to specific cell receptors, such as peroxisome proliferator-activated receptors (PPARs), which regulate inflammation. It may also interact with cannabinoid receptors, though indirectly, to reduce pain and inflammation.

PalmitoylEthanolamide Typical Uses

1, PalmitoylEthanolamide powder has been studied for its potential benefits in managing chronic pain conditions, such as neuropathic pain, osteoarthritis, and fibromyalgia. PEA has also been researched for its role in supporting immune function and reducing symptoms of inflammatory diseases.

2, PEA powder is sometimes used in topical formulations for skin care, such as creams for dermatitis and itching, which could also benefit scalp health. Improved scalp health might reduce hair loss and promote hair growth in some individuals.

3, Preliminary research has indicated that PEA might help improve mood and reduce anxiety in people with depression by influencing the endocannabinoid system and inflammatory pathways.

Pea vs. Luteolin

PEA and luteolin are sometimes combined in supplements, especially formulations designed to manage chronic inflammation and support brain health. The combination is believed to provide synergistic effects, where luteolin’s antioxidant and neuroprotective actions enhance PEA’s anti-inflammatory properties.

PEA focuses on pain relief and neuroprotection through immune modulation and inflammation reduction.

Luteolin offers broad antioxidant and anti-inflammatory benefits, with additional roles in allergy management, cancer prevention, and cardiovascular protection.

Palmitoylethanolamide (PEA) Supplements For Animals

Palmitoylethanolamide supplements are not only for humans but can also be used in pet nutrition.

More and more brands have launched related products and received positive feedback.

PEA animal supplements are gaining popularity for their anti-inflammatory, analgesic, and neuroprotective properties. These supplements are used to support various conditions, especially related to pain, inflammation, and aging in animals.

Relable Supplier of PalmitoylEthanolamide-Nutraflux

With a solid commitment to quality, Nutraflux consistently provides PEA that meets rigorous industry standards, making it a trusted partner for clients seeking top-tier ingredients.

Additionally, Nutraflux’s robust research and development capacity allows it to stay at the forefront of innovation, ensuring continuous product specification and formulation improvements.

If you are interested in PEA or have specific requirements regarding specifications and applications, please get in touch with us. Our R&D department will do its best to meet your needs and deliver the desired product.

Nutraflux PEA Products in stock

PEA Powder

PEA Micronized powder

PEA  Water Dispersed Powder

PEA Capsules

Technical Data Sheet
Product Information
Product Name: PalmitoylEthanolamide
CAS No.: 544-31-0
Molecular Weight: 299.5
Molecular Formular: C18H37NO2
Country of Origin: P.R. China
Item Specification Test Method
Active Ingredients
Assay(%,On Dried Base) NLT99.0% HPLC
Purity(%,On Dried Base) NLT99.0% HPLC
Physical Control
Appearance Crystalline Powder Visual
Color White to Off white Visual
Identification Positive IR&NMR
Water 1.0% Max CPh
Melting Point(°C) 98.0-100.0 CPh
Palmitoyldietanolamide Absent HPLC
Other total ethanolamides ≤1.0% HPLC
Total impurities ≤1.0% HPLC
Chemical Control
Heavy metals NMT10ppm Atomic Absorption
Lead (Pb) NMT 2ppm Atomic Absorption
Arsenic (As) NMT 1ppm Atomic Absorption
Cadmium(Cd) NMT 1ppm Atomic Absorption
Mercury(Hg) NMT 0.1ppm Atomic Absorption
Microbiological Control
Total Plate Count 1000cfu/g Max AOAC
Yeast & Mold 100cfu/g Max AOAC
Total Coliforms 10cfu/g Max AOAC
E.Coli Negative/10g AOAC
Salmonella sp. Negative/25g AOAC
Staph Aureus Negative/10g AOAC
Pseudomonas aeruginosa Negative/25g AOAC
Gram negative bateria bile-tolerants Negative/25g AOAC
Packing and Storage
Packing Pack in paper-drums and 2 plastic-bags inside.  25Kg/Drum
Storage Store in a well-closed container away from moisture and direct sunlight.  Store temperature, room temperature.
Shelf Life 2 years if sealed and stored properly.

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