Magnesium L Threonate

Product Name Magnesium L-Threonate
Other Name magnesium (2R,3S)-2,3,4-trihydroxybutanoate monohydrate
CAS Number 778571-57-6
Molecular Formula C8H14MgO10
Molecular Weight 294.5
Specifications 99%
Appearance/color White to off-white powder,
Application Dietary supplement
Bulk Package 25kg/drum
OEM services Available upon specific requirement

OEM MOQ: 500 Units
Place of Origin: 
China
Bulk Package: 25kg/drum
Port: Shanghai, China
Payment terms: T/T, Letter of Credit, Western Union

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What is Magnesium L Threonate?

Magnesium L threonate is a magnesium specifically designed to enhance brain health. It is the magnesium salt of L-chronic acid, a metabolite of vitamin C, and has been studied for its potential cognitive benefits. The critical feature of Magnesium L threonate is its ability to cross the blood-brain barrier more effectively than other forms of magnesium, making it particularly useful for improving brain function.

 Magnesium L Threonate Key Benefits:

  1. Improves Brain Magnesium Levels: It can raise magnesium concentrations in the brain more efficiently than other forms, which is critical for supporting neurological health.
  2. Cognitive Enhancement: Research suggests it may improve short-term and long-term memory, learning abilities, and cognitive function, especially in aging individuals.
  3. Neuroprotective Effects: Magnesium L-threonate may support brain health by promoting synaptic plasticity (the ability of brain cells to form new connections), vital for learning and memory retention.
  4. Potential Anti-Aging Properties: Some studies indicate that Magnesium L-threonate could slow cognitive decline and age-related brain changes.
  5. Supports Stress Reduction and Sleep: Magnesium has calming effects on the nervous system, and Magnesium L-threonate may help reduce anxiety, promote relaxation, and improve sleep quality.

How does magnesium l threonate work?

  • The critical feature of Magnesium L-threonate is its ability to cross the blood-brain barrier, a protective membrane that prevents many substances from entering the brain. This is what sets it apart from other forms of magnesium, which typically have limited access to brain tissues.
  • The L-threonate component (derived from vitamin C) enhances the bioavailability of magnesium in the brain, making it one of the most efficient forms of neurological benefits.

Magnesium vs Magnesium l threonate

Aspect Magnesium (General), Magnesium L-threonate
Primary Use Muscle, nerve, bone health, and general magnesium deficiency Cognitive function, memory enhancement, brain health
Absorption Rate Varies depending on the form (e.g., citrate has good absorption, oxide has poor absorption) High absorption in the brain due to crossing the blood-brain barrier
Effect on Brain Minimal brain-targeting effect; mainly supports physical health Specifically designed to increase magnesium levels in the brain
Cognitive Benefits Limited; not targeted explicitly for brain health Improves memory, learning, neuroplasticity, and cognitive function
Elemental Magnesium Content Higher in forms like citrate, oxide, or glycinate Lower elemental magnesium but better brain bioavailability
Common Uses General magnesium supplementation, digestive support, muscle relaxation, cardiovascular health General magnesium supplementation, digestive support, muscle relaxation, cardiovascular health
Laxative Effect Some forms (e.g., citrate, oxide) have a strong laxative effect Minimal to no laxative effect
Cost Generally less expensive Usually more expensive due to its specialized brain benefits

How to take Magnesium or Magnesium l threonate supplement?

Magnesium L-threonate is better if your primary goal is to support brain health, memory, and cognitive function or reduce brain aging. It’s particularly suited for people concerned about age-related cognitive decline or wanting to improve mental clarity and focus.

General Magnesium forms (like magnesium glycinate, magnesium citrate, or magnesium oxide) are better for muscle health, energy production, heart health, and relieving digestive issues (e.g., constipation). These are usually recommended for general magnesium deficiency.

Magnesium l – Threonate Dose

1,500 to 2,000 mg daily, typically divided into two or three doses.

Morning Dose: 1,000 mg in the morning

Evening Dose: 1,000 mg in the evening

This dosage provides about 144 mg of elemental magnesium, the actual magnesium content available for the body.

 

Technical Data Sheet
Product Information
Product Name: Magnesium L-Threonate
CAS No.: 778571-57-6
Molecular Formular: C8H14MgO10
Molecular Weight: 294.5
Item Specification Test Method
Active Ingredients
Assay(As Dried Base,%) ≥ 99% HPLC
Mg ( per 100g) 7.2-8.5g HPLC
Physical Control
Appearance Fine Powder Visual
Color White to Off White Visual
Odor &Taste Characteristic Organoleptic
Solubility Insoluble in methanol, and soluble in water  freely USP
Loss on Drying 2% Max USP
PH 6.0~8.0 USP
Particle size 95% pass 80 mesh USP
Chemical Control
                   Heavy metals                           NMT 10ppm                                            USP
Arsenic (As) NMT 2.0ppm ICP-MS
Lead (Pb) NMT 1.0ppm ICP-MS
                         Chlorides (Cd) NMT 0.5ppm ICP-MS
Mercury (Hg) NMT 0.5ppm ICP-MS
Microbiological Control
Total Plate Count 1000cfu/g Max AOAC
Yeast & Mold 100cfu/g Max AOAC
E.Coli  Negative AOAC
Salmonella  Negative AOAC
Staphy aureus Negative AOAC
Packing and Storage
Packing Pack in paper-drums and two plastic-bags inside.  25kg/Drum
Storage Store in a well-closed container away from moisture and direct sunlight.
Shelf Life 2 years if sealed and stored properly.

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